Efomycine U, a new C2-asymmetric elaiophylin derivative from Streptomyces malaysiensis DSM 4137.

Autor: Xu, Jing, Wu, Jingwan, Zhou, Dongdong, Zhang, Xuexia, Leadlay, Peter F.
Předmět:
Zdroj: Natural Product Research; Sep2024, Vol. 38 Issue 17, p3057-3062, 6p
Abstrakt: Chemical examination of an actinomycete strain Streptomyces malaysiensis DSM 4137 derived from a soil sample derived isolate Streptomyces sp. DSM 3816, yielded a new C2-asymmetric elaiophylin derivative efomycine U (1) and a known analogue halichoblelide D (2). These structures were unambiguously elucidated on the basis of extensive NMR spectroscopic and mass spectrometric analyses. All compounds isolated were subjected to antimicrobial, cytotoxic and immnosuppressive activities evaluation. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index