Autor: |
Xie, Xue, Zhang, Hongda, Liu, Lina, Ni, Fuyong, Yu, Xiao, Zhong, Yan, Yan, Ming, Zhang, Chenfeng, Wang, Zhenzhong, Xu, Nan, Xiao, Wei |
Předmět: |
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Zdroj: |
Natural Product Research; Sep2024, Vol. 38 Issue 17, p2941-2948, 8p |
Abstrakt: |
One new butylphthalide ligusticumolide H (1), together with the known butylphthalides senkyunolide I (2), senkyunolide H (3), (3 R,3′S)-3′-hydroxy-3-butylphthalide (4), (3 R)-4-hydroxy-3-butylphthalide (5) and senkyunolide C (6) was isolated from the rhizome of Ligusticum striatum DC. Their structures were determined by extensive spectroscopic analyses including HR-ESI-MS, 1D and 2D NMR, and the absolute configuration of 1 was established by NMR and ECD calculations. Their effect on NO production in IL-1β-stimulated chondrocytes was also evaluated. [ABSTRACT FROM AUTHOR] |
Databáze: |
Complementary Index |
Externí odkaz: |
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