EP12.07: Contribution of circulating neutrophil extracellular traps to endothelial dysfunction in pre‐eclampsia.

Autor: Borrell, M., Youssef, L., Ramos, A., Valle, M. Tortajada, Molina, P., Guillen, E., Martinez, J., Moreno‐Castaño, A., Escolar, G., Carreras, E., Gratacos, E., Diaz‐Ricart, M., Palomo, M., Crispi, F.
Předmět:
Zdroj: Ultrasound in Obstetrics & Gynecology; Sep2024 Supplement 1, Vol. 64, p238-238, 1p
Abstrakt: This article, titled "Contribution of circulating neutrophil extracellular traps to endothelial dysfunction in pre-eclampsia," explores the role of neutrophil extracellular traps (NETs) in pre-eclampsia-associated endothelial dysfunction. The study found that NETs obtained from pre-eclampsia patients triggered an oxidative, prothrombotic, and proinflammatory state in endothelial cells, leading to increased expression of VCAM-1, ICAM-1, and reactive oxygen species (ROS). These findings suggest that circulating NETs may contribute to the endothelial damage observed in pre-eclampsia. [Extracted from the article]
Databáze: Complementary Index