Post-Diarrheal Acute Kidney Injury During an Epidemic in Monsoon -- A Retrospective Study from a Tertiary Care Hospital.

Autor: Haridas, Nived, Thirumavalavan, S., Fernando, M. Edwin, Vellaisamy, Murugesan, Annadurai, Poongodi, Srinivasaprasad, N. D., Surendran, Sujit, Valavan, K. Thirumal, Joseph, Jerry, Gayathri, M. S.
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Zdroj: Indian Journal of Nephrology; Jul/Aug2024, Vol. 34 Issue 4, p338-343, 6p
Abstrakt: Background: Acute kidney injury (AKI) is a severe complication of acute diarrheal diseases; however, there is limited data on post-diarrheal AKI (PD-AKI) epidemiology and outcomes. This study aimed to investigate the clinicodemographic profile and outcomes of PD-AKI in our hospital. Materials and Methods: We retrospectively analyzed data from 93 patients admitted with PD-AKI during a diarrheal illness epidemic. Patients were stratified based on the Kidney Disease: Improving Global Outcomes (KDIGO) AKI stage and quick Sequential Organ Failure Assessment (qSOFA) score. Clinicodemographic data and outcomes were recorded and analyzed. Results: The mean age of the patients was 45.7 ± 11.9 years, with a majority being men (n = 55, 59%). All patients presented with watery diarrhea, 85% (n = 79) had vomiting, and 66% (n = 61) presented in shock. At presentation, 59% were oliguric, while 32% were anuric. KDIGO stage 3 AKI was observed in 71% (n = 66) of patients. Dialytic support was required in 29% (n = 27) of cases. The mortality rate was 6.5% (n = 6), mostly due to refractory shock, while the remaining patients recovered. Risk factor analysis demonstrated a higher qSOFA score, and peak serum creatinine levels were associated with an increased likelihood of requiring renal replacement therapy and delayed renal recovery. Conclusion: This study provides valuable insights into the clinicodemographic characteristics and outcomes of PD-AKI. The high prevalence of severe AKI emphasizes the importance of early recognition and appropriate management strategies for these patients. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index