Abstrakt: |
A recent report from the University of Notre Dame discusses the resistance of biofilms to antimicrobials and the potential for low-frequency ultrasound (LFU) to enhance the effectiveness of antibiotics. The study focused on Pseudomonas aeruginosa biofilms and found that biofilm physical characteristics, such as thickness and roughness, were linked to antimicrobial efficiency. LFU weakened the biofilm and increased antibiotic diffusivity, suggesting a potential "decohesion" effect. This research highlights the importance of understanding biofilm properties in developing strategies to combat chronic infections. [Extracted from the article] |