Researchers from Seattle Children's Research Institute Report Details of New Studies and Findings in the Area of Leukemia (Human Plasma Cells Engineered To Secrete Bispecifics Drive Effective In Vivo Leukemia Killing).

Předmět:	BISPECIFIC antibodies BLOOD cells MYELOID cells BLOOD proteins PLASMA cells
Zdroj:	Immunotherapy Weekly; 9/10/2024, p2896-2896, 1p
Abstrakt:	A study conducted by researchers at Seattle Children's Research Institute explores the use of bispecific antibodies for the treatment of acute leukemias. The study focuses on the secretion of bispecific antibodies by human plasma cells and their effectiveness in killing leukemia cells. The researchers found that plasma cells secreting anti-CD19-bispecific antibodies were able to control acute lymphoblastic leukemia in mice. The study suggests that engineered plasma cells could be a promising delivery system for the treatment of acute leukemias and potentially other cancers. [Extracted from the article]
Databáze:	Complementary Index
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