| Autor: |
Yanthi, Nova Dilla, Anggraeni, Anneke, Said, Syahruddin, Damayanti, Retno, Muladno |
| Předmět: |
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| Zdroj: |
AIP Conference Proceedings; 2024, Vol. 2970 Issue 1, p1-5, 5p |
| Abstrakt: |
The breastfeeding period until the barn is dry makes dairy cows vulnerable to bacterial attacks that can lead to udder infection. Infected bacteria in cows trigger an innate immune system reaction, including a cytokine rash and chemotactic. This activity aimed to analyze the gene expression profile of cytokines and chemokines in the blood of dairy cows infected with subclinical mastitis. Six genes are used: the TLR group (TLR 2 and TLR 4), the cytokine group (IL1A and IL6), and the chemokines group (IL8 and CXCR1). The expression was derived from the isolation of mRNA in the blood of 10 healthy cows infected with sub-clinical mastitis by RT-PCR. Sub-clinical mastitis control was conducted using the California Mastitis Test (CMT) method. Expression of immune marker genes IL6, IL8, TLR2, TLR4, and CXCR1 was observed more in healthy cow blood samples than in cows exhibiting signs of mastitis. whereas the IL1A gene is approximately equal between the two conditions. Inflammation of breast tissue in dairy cows modulates the expression of a number of genes associated with the innate immune system. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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