The anti-aging potential of peptides from fermented Nannochloropsis sp.

Autor: Ting Yang, Huawen Li, Xun Xu, Honghui Guo, Tangbin Zou, Enqin Xia
Předmět:
Zdroj: China Surfactant Detergent & Cosmetics (2097-2806); Aug2024, Vol. 54 Issue 8, p921-929, 9p
Abstrakt: The extraction and composition analysis of peptides (FNPs) from fermentation Nannochloropsis sp., as well as their anti-aging effects on Drosophila melanogaster in vivo were investigated. Compared with the non-fermentation group, the number of peptide in FNPs increases by about 100, and the oxidation sites in the peptides also increase. The maximum absorption intensity of FNPs is observed at 258 nm with a dose-dependent relationship. Compared with the control group, 5 μg/mL FNPs extends the mean life span of the the natural aging Drosophila melanogaster for 13 days. Additionally, for 70-90 days old, the deterioration of oxidative stress indicators such as MDA, SOD, and CAT caused by age are significantly restored and increased to the level of positive group by FNPs at 0.5 and 5 μg/mL. These results indicate that FNPs have potential as a promising nutritional component for alleviating human health problems induced by aging. It can also be used as a new antioxidant ingredient for functional food development or cosmeceutical applications from a resource rich and easily obtainable raw material Nannochloropsis sp. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index