The ethics of intra-amniotic drug administration in perinatal clinical practice.

Autor: Hong, Grace, Baden, Kyrie Eleyson, Olds, Rolanda, Injeti, Elisha, Muzzy, Julia, Cole, Justin W, Sullivan, Dennis
Předmět:
Zdroj: Clinical Ethics; Sep2024, Vol. 19 Issue 3, p271-276, 6p
Abstrakt: Providing in-utero treatments to target specific conditions in the fetus is a relatively new approach in perinatal care, with the vast majority of these treatments being used off-label. The high degree of off-label medication use in the perinatal and neonatal settings raises concern for the safety of both the fetuses and expectant mothers. This report presents two examples of intra-amniotic drug administration based on reported clinical cases. From the ethical framework of medical principlism, we examine the competing ethical duties of autonomy, beneficence, and non-maleficence in this setting. We then lay out three fundamental ethical principles for obtaining informed consent and maximizing clinical benefit. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index