Artemisinin and Its Derivatives as Potential Anticancer Agents.

Autor:	Wen, Luan, Chan, Ben Chung-Lap, Qiu, Ming-Hua, Leung, Ping-Chung, Wong, Chun-Kwok
Předmět:	ARTEMISININ derivatives ARTEMISIA annua ANTINEOPLASTIC agents HERBAL medicine ARTEMISININ
Zdroj:	Molecules; Aug2024, Vol. 29 Issue 16, p3886, 20p
Abstrakt:	Artemisinin is a natural sesquiterpene lactone obtained from the traditional Chinese medicinal herb Artemisia annua L. (qinghao). Artemisinin and its derivatives share an unusual endoperoxide bridge and are extensively used for malaria treatment worldwide. In addition to antimalarial activities, artemisinin and its derivatives have been reported to exhibit promising anticancer effects in recent decades. In this review, we focused on the research progress of artemisinin and its derivatives with potential anticancer activities. The pharmacological effects, potential mechanisms, and clinical trials in cancer therapy of artemisinin and its derivatives were discussed. This review may facilitate the future exploration of artemisinin and its derivatives as effective anticancer agents. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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