Expanding the Scope of Metal-Free Catalytic Approach for the Green One-Pot Multicomponent Synthesis of β-Amido Carbonyl Scaffolds.

Autor:	Ramya, K., Chakko, Seena, Shinu, V. S., Arun, S.
Předmět:	SUSTAINABLE chemistry ACETYL chloride ACETONITRILE KETONES CATALYSTS
Zdroj:	Russian Journal of Organic Chemistry; Jun2024, Vol. 60 Issue 6, p1123-1128, 6p
Abstrakt:	An efficient, mild, and green one-pot multicomponent synthetic approach has been proposed for the synthesis of β-amido carbonyl scaffolds via coupling of aromatic aldehydes, enolizable ketones, and acetonitrile in the presence of acetyl chloride and ammonium chloride as a metal-free highly effective catalyst. The developed approach provides a novel cost-effective and environmentally friendly route to access highly functionalized structural scaffolds in in good to excellent yields and requires less operational skill and conditions. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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