Synthesis of 2-azido-4-chloro-6-phenylpyrimidine-5-carbaldehyde and its transformations in DMSO.

Autor:	Aleksandrova, N. V., Nikolaenkova, E. B., Gatilov, Yu. V., Mamatyuk, V. I., Krivopalov, V. P.
Předmět:	VILSMEIER reagents NUCLEAR magnetic resonance spectroscopy X-ray spectroscopy X-ray diffraction ISOMERIZATION
Zdroj:	Russian Chemical Bulletin; Jul2024, Vol. 73 Issue 7, p2014-2022, 9p
Abstrakt:	2-Azido-4-chloro-6-phenylpyrimidine-5-carbaldehyde was synthesized by the Vilsmeier–Haack reaction. In DMSO, it transforms into 7-oxo-5-phenyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carbaldehyde and then undergoes isomerization recyclization into 6-benzoyltetrazolo[1,5-a]pyrimidin-7(4H)-one. The structures of the obtained compounds were determined by NMR spectroscopy and X-ray diffraction. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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