Researchers at Zhejiang University Release New Data on Apoptosis (Protective effects of Ganoderma lucidum spores on estradiol benzoate-induced TEC apoptosis and compromised double-positive thymocyte development).

Předmět:	T cell receptors ORGANIC compounds BENZOATES EPITHELIAL cells GANODERMA lucidum
Zdroj:	Drug Week; 9/6/2024, p2289-2289, 1p
Abstrakt:	A recent report from Zhejiang University in China discusses research on apoptosis, specifically focusing on the protective effects of Ganoderma lucidum spores (GLS) on thymic atrophy and T cell development. The study used a mice model to evaluate the impact of GLS on thymic damage caused by estradiol benzoate (EB). The researchers found that GLS effectively mitigated EB-induced thymic damage by reducing apoptotic thymic epithelial cells (TECs) and enhancing the output of CD4+ T cells. Additionally, GLS promoted T cell receptor rearrangement and facilitated the development of double-positive (DP) to invariant natural killer T (iNKT) cells. The study suggests that GLS has potential as a T-cell regeneration inducer. [Extracted from the article]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu