Abstrakt: |
Researchers from Federal University in Recife, Brazil have developed a method to quantify a novel indole-thiazole derivative (CS08) in nanoparticles. The method uses high-performance liquid chromatography (HPLC) coupled with a UV detector and has been validated for its selectivity, linearity, precision, accuracy, limit of detection (LOD), limit of quantification (LOQ), and robustness. The researchers were able to quantify CS08 in different matrices and evaluate its encapsulation rate in nanoparticles. The validated method is suitable for the quantification of CS08 and can be used in the development of pharmaceutical formulations. [Extracted from the article] |