New Findings from National Tsing-Hua University Update Understanding of Ovarian Cancer (Detection of Dual-methylated Brca1/brca2 Cell-free Dna for Ovarian Cancer On an Aptamer-based Integrated Microfluidic System).

Předmět:	CELL-free DNA NUCLEIC acid probes TUMOR suppressor genes CHEMICAL engineering NEWSPAPER editors OVARIAN cancer
Zdroj:	Women's Health Weekly; 9/6/2024, p643-643, 1p
Abstrakt:	Researchers at National Tsing-Hua University in Hsinchu, Taiwan have developed a new screening strategy to detect ovarian cancer. They used a systematic evolution of ligands by exponential enrichment (SELEX) process to select a methylation-specific aptamer that can capture methylated cell-free DNA (cfDNA) from the blood of ovarian cancer patients. This aptamer was then integrated into a microfluidic chip for rapid and automatic detection of methylated tumor suppressor genes. The researchers believe that this screening strategy could be used not only for ovarian cancer diagnosis but also for detecting DNA methylation in other types of cancer. [Extracted from the article]
Databáze:	Complementary Index
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