Autoimmune Hemolytic Anemia Associated With Myelodysplastic Syndrome: A Case Report.

Autor: Ribeiro, Leonardo, Nwanwene, Kemnasom, Anwar, Khurram, Abdallah, Mahmoud, Shenouda, Mina
Zdroj: Journal of Investigative Medicine High Impact Case Reports; 8/22/2024, p1-3, 3p
Abstrakt: Myelodysplastic syndrome (MDS) represents a spectrum of myeloid disorders occasionally linked to autoimmune diseases. Here, we present a case of a 60-year-old man demonstrating an unusual coexistence of MDS with warm-autoantibody autoimmune hemolytic anemia (wAIHA). Diagnostic evaluation, including positive direct antiglobulin testing, confirmed the autoimmune etiology of his anemia despite his low-risk MDS classification. Prompt initiation of prednisone therapy resulted in significant hematological and clinical improvement, allowing for a conservative management approach without transfusion requirements. This case underscores the importance of identifying the relationship between wAIHA and MDS, particularly in low-risk scenarios. Moreover, these findings suggest the efficacy of corticosteroids in managing autoimmune anemia in the context of concomitant wAIHA and MDS. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index