Abstrakt: |
A recent report from Ivanovo State University of Chemistry and Technology in Russia discusses the use of Schiff bases, compounds widely found in nature, in industry and biomedicine. Schiff bases are commonly used to identify metal ions and molecules, including proteins. However, their susceptibility to hydrolysis in water limits their applications. The report explores how the addition of hydroxyl or thiol groups to aromatic amine-bearing rings can increase the stability of Schiff bases in water. The study analyzes the spectral properties and kinetics of hydrolysis and formation of Schiff bases derived from pyridoxal 5'-phosphate and different aromatic amines. The research concludes by examining the changes in hydrolysis rate using computed values of local reactivity indices. [Extracted from the article] |