| Abstrakt: |
A recent study conducted by researchers at Czech University of Life Sciences Prague investigated the effectiveness of anti-inflammatory drugs in treating musculoskeletal infections caused by Staphylococcus aureus. The study found that celecoxib, an anti-inflammatory drug, exhibited the most potent antistaphylococcal effect against all tested strains of S. aureus, including methicillin-resistant strains. Additionally, the combination of celecoxib and oxacillin showed synergistic effects against S. aureus, including a significant reduction in the minimum inhibitory concentration of oxacillin. These findings suggest that celecoxib and its combination with oxacillin could be potential agents for the development of novel therapies for musculoskeletal infections caused by S. aureus. However, it is important to note that the concentrations of anti-inflammatory drugs used in the study were higher than those typically obtained in patients, and alternative methods of drug administration, such as a drug delivery system, may be necessary. [Extracted from the article] |
