| Autor: |
Pulligada, Syam Sundar, Chandrashekar, Poosarla, Kommalapati, Vatsalya, Kattappagiri, Kiran Kumar, Chandra, Lalith Prakash |
| Předmět: |
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| Zdroj: |
JIDA: Journal of Indian Dental Association; Jul2024, Vol. 18 Issue 7, p35-39, 5p |
| Abstrakt: |
Introduction: Diabetes mellitus is a clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of insulin. In the oral cavity, yeasts commonly colonize the tongue, palate, and buccal mucosa. Aside from oral mucosa, recent research have revealed the existence of C. albicans in other oral sites such as root canal, including persistent infection, carious lesions, and periodontal pockets.[5] The main aim of the study is to evaluate and compare Candidal colonization and species variation in healthy individuals and Diabetic patients. Material and Methods: Study includes 60 samples which are divided into Group -I consist of 30 Diabetic patients & Group II consists of 30 healthy individuals. Blood samples were collected to estimate the glucose levels using Glucose Tolerance Test & HbA1C. Saliva Sample was collected to estimate the candida using VITEK_2 Procedure. The absorbance values were measured on a digital calorimeter for Glucose Tolerance Test & HbA1C levels using the standard protocol. Results: Statistical Analysis was done using SPS software. Anova test & Paired t -test were done to estimate the comparison of Candidal positivity to HbA1C and VITEK_2 Procedure showed a mean of 97.33 and SD of 11.02 and with that of HbA1C, showed a mean of 4.93 and SD of 1.00. Comparison of study & control groups with VITEK2 status showed (46%) Candida albicans, followed by (16.67%) Candida famata and (10%) Candida tropicalis. Conclusion: The patients with diabetes mellitus are at a higher risk of developing oral Candidiasis. These members of the normal flora probably acquire invasiveness and become pathogenic leading to change in disease progression and develop resistance to the existing drug regime. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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