| Abstrakt: |
Close social connections are essential for mental and physical health and well-being at any age. A significant proportion of the world's population has experienced lockdown conditions due to the COVID-19 pandemic. There is a growing body of scientific literature on the adverse effects of social isolation on attention, memory, perception, executive function, and other aspects of cognitive processes. This can make people's daily lives more difficult, reducing their quality of life. This review seeks to systematize accumulated scientific data acquired in longitudinal population studies on the relationship between social isolation and the development of cognitive impairment in humans, and also analyzes data on the effects of social isolation of different durations on learning and memory processes obtained in experimental studies in animals. Questions are raised regarding the possible connection of these social isolation-induced disorders with changes in the functioning of one of the stress reactivity systems, i.e., the hypothalamic-pituitary-adrenal axis, and the immunoinflammatory response. [ABSTRACT FROM AUTHOR] |
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