CuBr2-mediated dehydrogenative [4+2] annulation of 1-naphthyl-1,3-indandiones and alkenes.

Autor: Zhang, Xu, Chang, Mengfan, Ni, Tongtong, Liu, Shuhan, Li, Wenguang, Xu, Xuefeng
Předmět:
Zdroj: Chemical Communications; 9/4/2024, Vol. 60 Issue 68, p9070-9073, 4p
Abstrakt: Intermolecular annulation reactions of 1-naphthyl-1,3-indandiones with alkenes proceed efficiently in the presence of a copper catalyst to generate spirocarbocycle compounds. Various spirocyclic molecules bearing an all-carbon quaternary center could be obtained by this novel method with good yields, excellent regioselectivity, and good functional group tolerance. A radical mechanism is proposed based on the HRMS analysis results of control experiments. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index