The Relationship Between Cardiac Energy Metabolism and Cardiac Function in Obesity and Type 2 Diabetes: Revisiting a 2003 Diabetes Classic by Aasum et al.

Autor: Ussher, John R., Aasum, Ellen
Předmět:
Zdroj: Diabetes; Sep2024, Vol. 73 Issue 9, p1373-1376, 4p
Abstrakt: This article discusses the relationship between cardiac energy metabolism and cardiac function in obesity and type 2 diabetes. It highlights the advancements in studying cardiac energy metabolism, including the use of imaging techniques and the discovery of fatty acids as the primary fuel source for the heart. The article revisits a classic study by Aasum et al. that examined how obesity and type 2 diabetes affect cardiac energy metabolism. The study found that alterations in cardiac energy metabolism can directly lead to cardiac dysfunction. These findings have had a significant impact on our understanding of cardiac energy metabolism in obesity and type 2 diabetes. The article also discusses potential targets for pharmacotherapy to alleviate cardiovascular disease associated with obesity and type 2 diabetes. Future research in this field aims to explore the molecular mechanisms underlying these metabolic alterations and their effects on cardiac function. [Extracted from the article]
Databáze: Complementary Index