| Autor: |
Atsushi Kaga, Hayate Saito, Mitsuhisa Yamano |
| Předmět: |
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| Zdroj: |
Chemical Communications; 8/28/2024, Vol. 60 Issue 67, p8920-8923, 4p |
| Abstrakt: |
Herein, we report acid/base-controlled and divergent deuteration of N-unsubstituted imidazoles in an imidazole-selective manner. This protocol enabled the deuteration of not only the 4-arylimidazoles but also the 2-arylimidazoles without labelling the aromatic rings. We demonstrated the advantages of this protocol by the synthesis of deuterated pharmaceuticals, which is difficult to achieve by means of transition metals. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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