| Autor: |
Cherif, Jaouhra, Raddaoui, Anis, Fraj, Ghofrane Ben, Laabidi, Asma, Souissi, Nada |
| Předmět: |
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| Zdroj: |
AIMS Biophysics; 2024, Vol. 11 Issue 2, p1-12, 12p |
| Abstrakt: |
Low-dose ionizing radiation can trigger a phenomenon known as hormesis in microorganisms, in which exposure to mild stressors like radiation results in beneficial adaptive responses. This study investigated the impact of low-dose X-rays on Escherichia coli 's viability and their potential influence on antibiotic susceptibility. The irradiated samples displayed increased bacterial viability compared to non-irradiated controls, with a significant increase observed at 5 and 10 mGy of X-ray radiation exposure. This suggests a stimulating effect of low-dose ionizing radiation on E. coli 's viability. To explore the correlation between viability and antibiotic susceptibility, we assessed the inhibition zone diameters for various antibiotics in non-irradiated and irradiated samples. The obtained results showed that the exposure of bacteria to low-dose ionizing radiation resulted in a significant reduction in the inhibition zone diameters for marbofloxacin, amoxicillin/clavulanic acid, ceftiofur, and cefoxitin. These findings suggest that low-dose X-ray radiation exposure can enhance E. coli 's viability and its ability to withstand antibiotics, raising potential concerns. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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