Nanchang University Researchers Report Recent Findings in Apoptosis (Polystyrene nanoplastics induce apoptosis, autophagy, and steroidogenesis disruption in granulosa cells to reduce oocyte quality and fertility by inhibiting the PI3K/AKT...).

Předmět:	MEDICAL sciences ENDOCRINE cells GRANULOSA cells BENZENE compound derivatives OVARIAN follicle OOGENESIS AUTOPHAGY
Zdroj:	Women's Health Weekly; 8/23/2024, p757-757, 1p
Abstrakt:	A recent report from Nanchang University discusses the reproductive harm caused by polystyrene nanoparticles (PS-NPs) in female animals. The study found that sustained exposure to PS-NPs disrupted ovarian functions and decreased oocyte quality, potentially contributing to lower female fertility in mice. The researchers discovered that PS-NPs deactivated the PI3K-AKT signaling pathway, leading to the activation of autophagy and apoptosis and the disruption of steroidogenesis in granulosa cells. The study emphasizes the need for further research on the effects of PS-NPs on female reproduction and potential methods to mitigate their toxicity. [Extracted from the article]
Databáze:	Complementary Index
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