| Abstrakt: |
A recent report from the University of Oklahoma discusses the development of a novel treatment strategy for metastatic breast cancer. The researchers have developed a targeted photosensitizer for photothermal therapy (PTT) using single-walled carbon nanotubes (SWCNTs) conjugated with Annexin A5 (ANXA5), a protein that binds to tumor cells. In vitro and in vivo experiments showed that this treatment strategy, when combined with immune stimulation using an anti-programmed cell death protein-1 checkpoint inhibitor, resulted in a relatively high survival rate (80% at 100 days) in mice with aggressive breast cancer. This research provides promising evidence for the potential of targeted carbon nanotube-mediated photothermal therapy in the treatment of breast cancer. [Extracted from the article] |
