| Abstrakt: |
A recent report from Alanya Alaaddin Keykubat University discusses new research on oral lichen planus (OLP), a chronic oral mucosal disease of unknown cause. The study aimed to investigate the role of Biglycan (BGN) in Toll-like receptors (TLR)2/4-CD14 and TLR4-CD44 mediated signaling mechanisms in the pathogenesis of OLP. The findings showed that the gene expression of BGN, TLR2, TLR4, and CD14 was higher in OLP tissues compared to the control group, indicating activation of inflammation signaling and inhibition of autophagy in OLP. This study provides new insights into the mechanisms underlying OLP and highlights potential targets for future therapeutic interventions. [Extracted from the article] |
