Abstrakt: |
A study conducted by researchers at Zhejiang University School of Medicine in Hangzhou, China, explores the dynamic pattern of bile acids (BAs) in pediatric non-alcoholic fatty liver disease (NAFLD). The study found that dysregulation of BAs contributes to the development of NAFLD. During an oral glucose tolerance test (OGTT), conjugated BAs increased while unconjugated ones decreased after glucose uptake. Certain BAs were responsive to glucose in NAFLD, and primary BAs were increased while secondary BAs were decreased. The study suggests that variations in specific BAs may serve as potential diagnostic and therapeutic targets for NAFLD. [Extracted from the article] |