| Abstrakt: |
Researchers at Umm Al-Qura University have developed a spectrophotometric method for quantifying the antiepileptic medication retigabine in its pure form and pharmaceutical formulations. The method utilizes N-bromosuccinimide as an oxidizing agent and three dyes (amaranth, methylene blue, and indigo carmine) to measure the absorbance at specific wavelengths. The method showed high accuracy, precision, and reproducibility, with no interference from tablet excipients. The reliability of the method was confirmed through recovery studies and statistical analysis. This research provides a validated approach for estimating retigabine in pharmaceutical formulations. [Extracted from the article] |
