Gut microbes implicated in bladder cancer.

Předmět:
Zdroj: Drug Week; 8/13/2024, p425-425, 1p
Abstrakt: A new study by researchers at the European Molecular Biology Laboratory and the University of Split in Croatia has found that gut microbes may play a role in the development of bladder cancer. The researchers discovered that mice exposed to a carcinogen called BBN were less likely to develop tumors if they were also given antibiotics that killed 99.9% of their gut bacteria. Further investigation revealed that certain bacteria in the gut can convert BBN into a compound called BCPN, which triggers tumor formation. The researchers also found that human gut bacteria can convert BBN to BCPN, but there are individual differences in the ability of the microbiome to do so. The study suggests that a person's gut microbiome may influence their risk of developing chemically induced cancers and could potentially be used to predict and prevent cancer development. However, the researchers caution that cancer is a complex disease with multiple causes, and more research is needed to fully understand the role of the microbiome in cancer development. [Extracted from the article]
Databáze: Complementary Index