| Autor: |
Anderson, Steven, Dev, Sheena, Keller, Bruce, Khader, Alaa, Bell, Suzanne |
| Předmět: |
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| Zdroj: |
Aerospace Medicine & Human Performance; Aug2024, Vol. 95 Issue 8, p571-571, 1/3p |
| Abstrakt: |
INTRODUCTION: Decompression Sickness (DCS) is a risk during spaceflight extravehicular activities (EVAs). The NASA Exploration Atmosphere (EA) study aims to validate modeling efforts for a novel prebreathe protocol while adequately mitigating risk of DCS. We examined effects of exposure to the mild hypobaric hypoxic chamber environment on behavioral health and performance outcomes in Exploration Atmosphere Mission 2 (EA-2). METHODS: Eight participants spent 11 days in NASA's 20-foot chamber at Johnson Space Center (May--June 2023) where they were exposed to an atmosphere consisting of lower pressure (8.2 psia) and higher O2 (34%), controlling physiologic levels of N2. One participant left the study at Test Day 3. Participants completed five simulated EVAs during the 11-day test phase. Cognitive performance was measured using the Cognition test battery comprising 10 subtests. Cognitive performance results were examined during pre-test, 11-day test, and post-test phases to identify whether the mild hypobaric hypoxic environment substantially impacted participants' cognitive performance. Cognition test battery outcomes were corrected for practice and battery effects, and then z-transformed based on the average and standard deviation of baseline (pre-test) performance scores across study subjects. Summary scores for accuracy and speed were calculated by averaging across z-transformed scores within the accuracy and speed domain. RESULTS: Examining z-scores for outcomes in each of the 10 cognitive subtests indicated that participants' cognitive performance did not substantially change from baseline during the 11-day test or post-test phases in EA-2. Computed z-scores indicated that performance outcomes during 11-day test and post-test phases were all within one standard deviation of the group baseline mean. DISCUSSION: The small changes in cognitive performance observed from pre-test to 11-day test, and pre-test to post-test phases suggest that the mild hypobaric hypoxic environment did not substantially impact participants' cognitive performance. Future directions include combining results from multiple EA missions to increase sample size and conducting linear mixed effects models to compare performance across test phases. Learning Objectives 1. The audience will learn about the NASA Exploration Atmosphere study aims and objectives. 2. The audience will learn about. the cognitive and behavioral impacts of mild hypoxia. 3. The audience will learn about the cognitive and behavioral impacts of mild hypoxia as studied in NASA Exploration Atmosphere. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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