| Autor: |
Takahashi, Masakazu, Tsujimoto, Kazuhisa, Kato, Youichi, Yamada, Hideyuki, Takagi, Hiroshi, Nakamori, Shigeru |
| Předmět: |
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| Zdroj: |
Biotechnology Letters; Jul2005, Vol. 27 Issue 13, p893-897, 5p |
| Abstrakt: |
Sericin is the silk protein enveloping fibroin fibers in cocoons. Sericin hydrolysate protects cultured Sf9 insect cells from death caused by serum deprivation; the activity depends on the repeats of 38 amino acids. A partial peptide from the 38 residues, SGGSSTYGYS, inhibited serum-deprivation death as well. Cell viabilities in the presence of 10% (v/v) foetal calf serum, no additives and 1 m M SGGSSTYGYS were 96, 12 and 31% on the third day after inoculation, respectively. Aromatic residues seemed to be important because SGGSSTWGWS had the same activity as SGGSSTYGYS but SGGSSTAGAS had no activity. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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