| Autor: |
Pisano, Giusi, Wendler, Thomas, Valdés Olmos, Renato A., Garganese, Giorgia, Rietbergen, Daphne D. D., Giammarile, Francesco, Vidal-Sicart, Sergi, Oonk, Maaike H. M., Frumovitz, Michael, Abu-Rustum, Nadeem R., Scambia, Giovanni, Rufini, Vittoria, Collarino, Angela |
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| Zdroj: |
European Journal of Nuclear Medicine & Molecular Imaging; Aug2024, Vol. 51 Issue 10, p3026-3039, 14p |
| Abstrakt: |
Purpose: The aim of this review is to give an overview of the current status of molecular image–guided surgery in gynaecological malignancies, from both clinical and technological points of view. Methods: A narrative approach was taken to describe the relevant literature, focusing on clinical applications of molecular image–guided surgery in gynaecology, preoperative imaging as surgical roadmap, and intraoperative devices. Results: The most common clinical application in gynaecology is sentinel node biopsy (SNB). Other promising approaches are receptor-target modalities and occult lesion localisation. Preoperative SPECT/CT and PET/CT permit a roadmap for adequate surgical planning. Intraoperative detection modalities span from 1D probes to 2D portable cameras and 3D freehand imaging. Conclusion: After successful application of radio-guided SNB and SPECT, innovation is leaning towards hybrid modalities, such as hybrid tracer and fusion of imaging approaches including SPECT/CT and PET/CT. Robotic surgery, as well as augmented reality and virtual reality techniques, is leading to application of these innovative technologies to the clinical setting, guiding surgeons towards a precise, personalised, and minimally invasive approach. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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