| Autor: |
Mishra, Km Aditi, Rani, Manjoo, Rastogi, Munish |
| Předmět: |
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| Zdroj: |
Journal of Experimental Zoology India; Jul2024, Vol. 27 Issue 2, p1679-1686, 8p |
| Abstrakt: |
The emergence of antibiotic-resistant microbes has become an increasingly worrisome issue in recent years. Consequently, researchers have shifted their focus towards plants to uncover potential novel antibacterial chemicals. Gallic acid and tannic acid have been documented to possess many positive benefits, such as anti-inflammatory, antioxidant and antineoplastic qualities. The capacity of certain plant secondary metabolism products to function as tolerance-modifying compounds is a potential area for addressing the proliferation of infection resistance. An extensive investigation of the antibacterial effectiveness of phytochemicals on the clinical isolates of UTI microflora, highlighting their potential as a valuable component. This study was conducted in the Department of Medical Microbiology at Chhatrapati Shahu Ji Maharaj University (CSJMU), Kanpur over one year, specifically from October 2022 to October 2023. It was a cross-sectional study. A sterile widemouth container was used to collect a total of 350 freshly voided midline samples of urine from individuals whose initial routine urine tests showed positive results for pus cells and albumin. The phytochemical standards were obtained from Merck, St. Louis, MO, USA. Stock solutions of phytochemicals were prepared by dissolving 50 mg of each compound in 1 mL of phosphatebuffered saline (PBS) containing 10% DMSO. These solutions were used to figure out the antimicrobial susceptibility test. In the present study, it was observed that the tannic acid was more effective as compared to the gallic acid and other phytochemicals. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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