| Abstrakt: |
A new study conducted by researchers from Virginia Commonwealth University explores the effects of cathepsin B inhibition in cases of diffuse traumatic brain injury (TBI) and secondary intracranial pressure (ICP) elevation. The study, which used adult male rats, found that while cathepsin B is not directly responsible for membrane disruption, the administration of a cathepsin B inhibitor altered cathepsin B localization and reduced hypersensitivity. These findings highlight the importance of cathepsin B in late secondary pathologies associated with TBI. The study provides valuable insights into the potential role of cathepsin B in brain injury and could contribute to the development of new treatment strategies. [Extracted from the article] |
