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| Zdroj: |
Stem Cell Week; 8/8/2024, p2127-2127, 1p |
| Abstrakt: |
A new report discusses research findings on stem cell research conducted at the University of Tubingen in Germany. The study focuses on pontocerebellar hypoplasia type 2a (PCH2a), an ultra-rare pediatric disorder with limited treatment options. The researchers developed human models of PCH2a using regionalized neural organoids and found that PCH2a cerebellar organoids were reduced in size compared to controls, mirroring clinical neuroimaging findings. The study provides a foundation for understanding brain region-specific disease mechanisms and suggests a neurodevelopmental aspect of PCH2a. [Extracted from the article] |
| Databáze: |
Complementary Index |
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