Avacopan's potential to decrease MPO-ANCA titres concurrent with ameliorated activity in ANCA-associated vasculitis.

Autor: Tomoki Taniguchi, Ryosuke Hiwa, Mikihito Shoji, Eriho Yamaguchi, Mirei Shirakashi, Hideo Onizawa, Hideaki Tsuji, Koji Kitagori, Ran Nakashima, Shuji Akizuki, Akira Onishi, Hajime Yoshifuji, Masao Tanaka, Akio Morinobu
Předmět:
Zdroj: Modern Rheumatology Case Reports; Jul2024, Vol. 8 Issue 2, p314-317, 4p
Abstrakt: This article discusses the potential of avacopan, a medication that blocks a specific receptor, to improve the condition of patients with a type of blood vessel inflammation called ANCA-associated vasculitis. The article presents a case study of a patient who had high levels of a specific antibody despite treatment with other medications. However, when avacopan was added to their treatment, the antibody levels decreased. The authors suggest that avacopan may have the potential to lower antibody levels and improve the condition, but more research is needed. The article also provides information about conflicts of interest, funding, patient consent, and data availability. [Extracted from the article]
Databáze: Complementary Index