A case of subarachnoid haemorrhage associated with MPO-ANCA-positive eosinophilic granulomatosis with polyangiitis, successfully treated with glucocorticoid, cyclophosphamide, and mepolizumab.

Autor:	Yuki Satake, Shunsuke Sakai, Tetsuro Takao, Takako Saeki
Předmět:	CHURG-Strauss syndrome MICROSCOPIC polyangiitis BLOOD diseases SYMPTOMS CEREBRAL arteriovenous malformations HYPEREOSINOPHILIC syndrome
Zdroj:	Modern Rheumatology Case Reports; Jul2024, Vol. 8 Issue 2, p310-313, 4p
Abstrakt:	This article discusses a case of subarachnoid hemorrhage (SAH) associated with eosinophilic granulomatosis with polyangiitis (EGPA), a rare autoimmune disease. The patient experienced SAH along with other symptoms such as purpura, peripheral neuropathy, lung lesions, and rapidly progressive glomerulonephritis. Treatment included immunosuppressive therapy and the use of mepolizumab, a monoclonal antibody. The article highlights the importance of recognizing SAH as a potentially fatal complication of EGPA and the need for prompt treatment. Further research is needed to evaluate the effectiveness of mepolizumab for CNS involvement in EGPA. [Extracted from the article]
Databáze:	Complementary Index
Externí odkaz:	Zobrazit plný text záznamu