Epidemiology of Myelomeningocoele in Africa: An Experience in a Regional Neurosurgical Center in Northern Nigeria.

Autor:	Olayere Obanife, Henry, Jinjiri Nasiru, Ismail, Lagbo, Jacob, Otorkpa, Ega Joseph, Bala Shehu, Bello
Předmět:	COMMUNITY health services RISK assessment COOKING SPINA bifida ACADEMIC medical centers HYDROCEPHALUS PSYCHOLOGY of fathers SURGICAL clinics WOUND infections FOOD irradiation DESCRIPTIVE statistics LONGITUDINAL method PRENATAL care PSYCHOLOGY of mothers LUMBAR vertebrae PARITY (Obstetrics) FOLIC acid deficiency MOTHERHOOD FIRST trimester of pregnancy LITERACY DATA analysis software DISEASE incidence DIETARY supplements THORACIC vertebrae POVERTY DISEASE risk factors DISEASE complications PREGNANCY
Zdroj:	Journal of Pediatric Neurosciences; Jul-Sep2022, Vol. 17 Issue 3, p237-243, 7p
Abstrakt:	Background: Myelomeningocoele is a common birth defect with strong associations with folate deficiency and maternal illiteracy. The aim of this study is to describe the distribution and pattern of myelomeningocoele in a resource-poor community and determine the factors responsible for the rising incidence in Africa. Patients and Methods: Prospective cohort study of 90 patients with myelomeningocoele who were treated at the Regional Centre for Neurosurgery (RCNS), Sokoto between September 2015 and December 2016. Data were collected through a structured questionnaire and analyzed by using SPSS 21 version. Results: Ninety patients were recruited into this study with a male: female ratio of 1:1 and a mean age of 102±213 days at presentation. The majority of patients' mothers were between 19 and 35 years of age, with 70% having no formal education; however, most of the patients' fathers were either unskilled casual workers or subsistent farmers (56.7%). Of the 36.7% of the patients' mothers who had antenatal care, only 35.6% of them took a folic acid supplement mostly after the first trimester. More than 90% of the mothers had persistent sources of heat irradiation during pregnancy, majorly from firewood cooking. Most of the myelomeningocoele (MMC) sacs (72.9%) were located in the lumbar and sacral regions. Wound infection was the most common complication (50.0%), whereas trans-fontanelle ultrasound scan (TFUSS) showed hydrocephalus in 45.6% of patients. Conclusion: Myelomeningocoele is a common medical problem with increased incidence in poor countries. Poverty and illiteracy play major roles in its occurrence, and challenges are faced with its prevention and management. Longtime exposure to heat from firewood cooking and multiparity were identified as significant risk factors for myelomeningocoele. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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