Effectiveness of Treatment Approaches in COVID-19 Pneumonia: A Comparative Evaluation between a Specialized Center and Conventional Hospitals.

Autor:	Romero Pareja, Rodolfo, Ruiz Grinspan, Martín S., Castro Arias, María Lorena, García Hernández, Raquel, Martín Sánchez, Francisco Javier, Álvarez-Rodríguez, Esther, Álvarez Rodríguez, Virginia, Minguens, Iria, Martínez Molina, Ana María, Torres Santos-Olmo, Rosario, Aranda, Sixto, Torres Rodríguez, Enrique, Gimeno Galindo, Carmen, Thuissard-Vasallo, Israel J, Marco Martínez, Javier
Předmět:	ANTIBIOTICS CROSS-sectional method IMMUNIZATION ANTICOAGULANTS ADRENOCORTICAL hormones KIDNEY failure MEDICAL quality control IMMUNOSUPPRESSIVE agents SCIENTIFIC observation HOSPITAL care QUESTIONNAIRES DISEASE management COVID-19 testing POLYMERASE chain reaction RESPIRATORY insufficiency MEDICAL care TREATMENT effectiveness HOSPITAL emergency services HOSPITALS MULTIVARIATE analysis SEVERITY of illness index HOSPITAL mortality COVID-19 vaccines TRANSFER of training GLASGOW Coma Scale HEART failure DESCRIPTIVE statistics CHI-squared test MANN Whitney U Test VIRAL pneumonia LONGITUDINAL method OPERATIVE surgery VACCINATION coverage ANTIVIRAL agents KAPLAN-Meier estimator ODDS ratio ARTIFICIAL respiration SEPSIS INTENSIVE care units OBSTRUCTIVE lung diseases HEALTH facilities LENGTH of stay in hospitals PUBLIC health COMPARATIVE studies DATA analysis software CONFIDENCE intervals COVID-19 pandemic COVID-19 COGNITION OVERALL survival OBESITY NONPARAMETRIC statistics DISEASE complications
Zdroj:	Healthcare (2227-9032); Jul2024, Vol. 12 Issue 14, p1365, 12p
Abstrakt:	Background: The early stages of the COVID-19 pandemic overwhelmed general hospitals in Spain. In response, a dedicated hospital for COVID-19 care, the Hospital de Emergencias Enfermera Isabel Zendal (HEEIZ), was established. This study aimed to compare clinical outcomes of COVID-19 patients treated at the specialized HEEIZ with those at conventional general hospitals (CGHs) in Madrid, Spain. Methods: The study was a prospective, observational cohort study including COVID-19 patients admitted to the HEEIZ and 14 CGHs (December 2020 to August 2021). Patients were assigned based on hospital preference. Clinical data were collected and analyzed using multivariate regression to assess primary and secondary outcomes, including hospital mortality, need of invasive mechanical ventilation (IMV), and pharmacological treatments. Results: The HEEIZ cohort (n = 2997) was younger and had lower Charlson comorbidity scores than the CGH cohort (n = 1526). Adjusted HEEIZ hospital mortality was not significantly higher compared with CGHs (OR: 1.274; 95% CI: 0.781–2.079; p = 0.332). Conclusions: During the study period, patients admitted to the HEEIZ showed no significant differences in clinical outcomes, compared with patients admitted at CGHs. These results might support the use of specialized centers in managing pandemic surges, allowing CGHs to handle other needs. [ABSTRACT FROM AUTHOR]
Databáze:	Complementary Index
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