| Autor: |
FAN Yu-Wei, ZHANG Yi-Jia, WEN He-Mei, YAN Hong, SHEN Wei, DING Yue-Qin, LONG Yun-Feng, ZHANG Zhi-Gang, LI Gui-Fang, JIANG Hong, RAO Hong-Ping, QIU Jian-Wu, WEI Xian, ZHANG Ya-Yu, ZENG Ji-Bin, ZHAO Changdoi, Liang, XU Wei-Peng, WANG Fan, YUAN Li |
| Předmět: |
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| Zdroj: |
Chinese Journal of Contemporary Pediatrics; Jun2024, Vol. 26 Issue 6, p611-618, 8p |
| Abstrakt: |
Objective To investigate the risk factors for bronchopulmonary dysplasia (BPD) in twin preterm infants with a gestational age of <34 weeks, and to provide a basis for early identification of BPD in twin preterm infants in clinical practice. Methods A retrospective analysis was performed for the twin preterm infants with a gestational age of <34 weeks who were admitted to 22 hospitals nationwide from January 2018 to December 2020. According to their conditions, they were divided into group A (both twins had BPD), group B (only one twin had BPD), and group C (neither twin had BPD). The risk factors for BPD in twin preterm infants were analyzed. Further analysis was conducted on group B to investigate the postnatal risk factors for BPD within twins. Results A total of 904 pairs of twins with a gestational age of <34 weeks were included in this study. The multivariate logistic regression analysis showed that compared with group C, birth weight discordance of >25% between the twins was an independent risk factor for BPD in one of the twins (OR=3.370, 95%CI: 1.500-7.568, P<0.05), and high gestational age at birth was a protective factor against BPD (P<0.05). The conditional logistic regression analysis of group B showed that small-for-gestational-age (SGA) birth was an independent risk factor for BPD in individual twins (OR=5.017, 95%CI: 1.040-24.190, P<0.05). Conclusions The development of BPD in twin preterm infants is associated with gestational age, birth weight discordance between the twins, and SGA birth. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
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