| Abstrakt: |
A recent study conducted by researchers at the Chinese University of Hong Kong has shed light on the role of ubiquitination, a post-translational modification, in cancer. The study found that E3 ubiquitin ligases, which regulate the specificity of ubiquitination for substrates, are up-regulated and exhibit reduced tissue specificity in tumors. The researchers also identified specific E3 ligases that are associated with tumor cell proliferation and metastasis, as well as those that serve as biomarkers for a favorable prognosis. This research highlights the potential of leveraging multi-omics data to identify prognosis biomarkers and potential drug targets for cancer therapy. [Extracted from the article] |
