| Abstrakt: |
A recent study conducted by researchers from Capital Medical University explores the role of autophagy in aging-related changes during orthodontic tooth movement in rats. The study found that autophagy plays an important role in regulating orthodontic tooth movement and is involved in aging-related changes. The researchers used immunohistochemistry, immunofluorescence, and staining techniques to measure the expression levels of osteogenesis, autophagy, aging factors, and osteoclast number in the periodontal membrane of rats. They also injected an autophagy activator called rapamycin and found that it increased autophagy, accelerated tooth movement, and reduced the levels of aging factors. The study concludes that autophagy may play a substantial role in regulating aging-related changes in orthodontic tooth movement. [Extracted from the article] |
