Initial Heart Rate Predicts Functional Independence in Patients With Spinal Cord Injury Requiring Surgery: A Registry-Based Study in a Mature Trauma System Over the Past 10 Years.

Autor: Mouchtouris, Nikolaos, Luck, Trevor, Yudkoff, Clifford, Hines, Kevin, Franco, Daniel, Al Saiegh, Fadi, Thalheimer, Sara, Khanna, Omaditya, Prasad, Srinivas, Heller, Joshua, Harrop, James, Jallo, Jack
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Zdroj: Global Spine Journal; Jul2024, Vol. 14 Issue 6, p1745-1752, 8p
Abstrakt: Study Design: Retrospective Cohort Study. Objectives: To determine the ability of early vital sign abnormalities to predict functional independence in patients with SCI that required surgery. Methods: A retrospective analysis of data extracted from the Pennsylvania Trauma Outcome Study database. Inclusion criteria were patients >18 years with a diagnosis of SCI who required urgent spine surgery in Pennsylvania from 1/1/2010-12/31/2020 and had complete records available. Results: A total of 644 patients met the inclusion criteria. The mean age was 47.1 ± 14.9 years old and the mean injury severity score (ISS) was 22.3 ± 12.7 with the SCI occurring in the cervical, thoracic, and lumbar spine in 61.8%, 19.6% and 18.0%, respectively. Multivariable logistic regression analyses for predictors of functional independence at discharge showed that higher HR at the scene (OR 1.016, 95% CI 1.006-1.027, P =.002) and lower ISS score (OR.894, 95% CI.870-.920, P <.001) were significant predictors of functional independence. Similarly, higher admission HR (OR 1.015, 95% CI 1.004-1.027, P =.008) and lower ISS score (OR.880, 95% CI 0.864-.914, P <.001) were significant predictors of functional independence. Peak Youden indices showed that patients with HR at scene >70 and admission HR ≥83 were more likely to achieve functional independence. Conclusions: Early heart rate is a strong predictor of functional independence in patients with SCI. HR at scene >70 and admission HR ≥83 is associated with improved outcomes, suggesting lack of neurogenic shock. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index