| Autor: |
Jimoh, A. A., Fatokun, B. O., Osuagwuh, U. I., Raheem, K. A. |
| Předmět: |
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| Zdroj: |
Journal of Sustainable Veterinary & Allied Sciences; Jun2024, Vol. 6 Issue 2, p143-148, 6p |
| Abstrakt: |
Implantation failure constitutes one of the major causes of pregnancy loss in all mammalian species. The complexity of implantation mechanism involves series of hormones, macromolecules, cytokines, chemokines, growth factors and repertoire of genes, however, progesterone receptor through which physiological responses to progesterone are initiated is the most essential for implantation across all mammalian species. Progesterone is also known as hormone of pregnancy because of its crucial roles to establish and sustain pregnancy and implantation. Progesterone facilitates blastocyst implantation to the maternal endometrium by promoting uterine secretion for conceptus growth and development, initiating window of receptivity, inducing quiescence and non-contractility of endometrium to avoid abortion and protection of embryo against maternal immune system. The aforementioned roles of progesterone and their mechanisms are the subject matter of this review. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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