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| Zdroj: |
Gastroenterology Week; 7/22/2024, p373-373, 1p |
| Abstrakt: |
A recent study conducted at the University of Sydney explores the role of the vitamin D receptor (VDR) in liver regeneration after partial hepatectomy in male mice. The researchers found that mice lacking hepatocyte VDR had impaired liver regeneration and hepatocyte proliferation, along with changes in bile salts and gene expression related to liver function and cell cycle regulation. These findings suggest that VDR plays a crucial role in hepatocytes during liver regeneration and that vitamin D deficiency may lead to reduced hepatocyte proliferation and fibrosis, compromising liver function. This research provides valuable insights into the potential impact of vitamin D on liver health. [Extracted from the article] |
| Databáze: |
Complementary Index |
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