Pre-Existing Immunity to a Nucleic Acid Contaminant-Derived Antigen Mediates Transaminitis and Resultant Diminished Transgene Expression in a Mouse Model of Hepatic Recombinant Adeno-Associated Virus-Mediated Gene Transfer.

Autor: Brimble, Mark A., Morton, Christopher L., Winston, Stephen M., Reeves, Isaiah L., Spence, Yunyu, Cheng, Pei-Hsin, Zhou, Junfang, Nathwani, Amit C., Thomas, Paul G., Souquette, Aisha, Davidoff, Andrew M.
Zdroj: Human Gene Therapy; Jul2024, Vol. 35 Issue 13/14, p477-489, 13p
Databáze: Complementary Index