Findings in Central Nervous System Agents Reported from University of Baghdad (Formulation and Development of Frovatriptan Succinate In Situ Gel for Nasal Drug Delivery: in Vitro and ex Vivo Evaluation).

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Zdroj: Drug Week; 7/22/2024, p801-801, 1p
Abstrakt: A recent study conducted at the University of Baghdad in Iraq has explored the formulation and development of a nasal drug delivery system for Frovatriptan, an antimigraine agent. The researchers aimed to create a dosage form that specifically targets the brain while minimizing systemic adverse effects. They successfully developed a mucoadhesive Frovatriptan-binary ethosome-loaded nasal in situ gel, which demonstrated favorable outcomes in terms of spreadability, drug content, mucoadhesive strength, release, and permeability. The study concludes that this nasal gel could be an effective method for treating migraines. The research has been peer-reviewed and published in the Pakistan Journal of Pharmaceutical Sciences. [Extracted from the article]
Databáze: Complementary Index
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