Gold-catalyzed cyclization and cycloaddition in natural product synthesis.

Autor: Lin, Boxu, Liu, Tianran, Luo, Tuoping
Předmět:
Zdroj: Natural Product Reports; Jul2024, Vol. 41 Issue 7, p1091-1112, 22p
Abstrakt: Covering: 2016 to mid 2023 Transition metal catalysis, known for its remarkable capacity to expedite the assembly of molecular complexity from readily available starting materials in a single operation, occupies a central position in contemporary chemical synthesis. Within this landscape, gold-catalyzed reactions present a novel and versatile paradigm, offering robust frameworks for accessing diverse structural motifs. In this review, we highlighted a curated selection of publications in the past 8 years, focusing on the deployment of homogeneous gold catalysis in the ring-forming step for the total synthesis of natural products. These investigations are categorized based on the specific ring formations they engender, accentuating the prevailing gold-catalyzed methodologies applied to surmount intricate challenges in natural products synthesis. [ABSTRACT FROM AUTHOR]
Databáze: Complementary Index