| Autor: |
Rifaldi, Sukandar, Edwin R., Fadlan, Arif, Fatmawati, Sri, Purnomo, Adi S., Wairata, Johanis, Ersam, Taslim |
| Předmět: |
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| Zdroj: |
Natural Product Research; Aug2024, Vol. 38 Issue 15, p2697-2702, 6p |
| Abstrakt: |
In our continuation of exploring antidiabetic agents from Garcinia species, we found that the methanolic extract of G. macrantha A.C.Sm. exhibited considerable α-glucosidase inhibition of 58.20 ± 0.37% in sucrose substrate and 39.86 ± 2.07% in maltose substrate at 100 μg/mL. Phytochemical investigation on the extract revealed the presence of a new biphenyl, macrabiphenyl A, which was successfully elucidated by means of spectroscopic methods (HRESIMS and 1D and 2D NMR). The α-glucosidase inhibitory evaluation indicated that the new compound was weakly active against the enzyme. [ABSTRACT FROM AUTHOR] |
| Databáze: |
Complementary Index |
| Externí odkaz: |
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